In Reply The secondary analysis of European Study Group for Pancreatic Cancer 4 (ESPAC-4) demonstrated that there were no significant differences between the time to recurrence and subsequent and overall survival between local and distant recurrence.¹ Patients with metastases to the lungs had a much longer survival compared with those with local recurrence or metastases to other sites such as the liver. Thus, it is clear that pancreatic cancer appears to behave as a systemic disease requiring effective systemic therapy after resection.

中文翻译：

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胰腺导管腺癌切除术后复发。

在答复中，欧洲胰腺癌研究小组4（ESPAC-4）的二级分析表明，复发时间与局部和远距复发之间的后续生存时间和总体生存率之间无显着差异。¹与局部复发或转移到其他部位（例如肝脏）的患者相比，肺转移的患者的生存期更长。因此，很明显，胰腺癌表现为一种全身性疾病，需要在切除后进行有效的全身治疗。