AIMS This field experiment examined whether trained people with type 1 diabetes mellitus (T1D) have similar cardiovascular and baroreflex alterations after a 21-km running race when compared to healthy people. METHODS Nine T1D (39.0 ± 11.1 yr; 175.0 ± 10.2 cm; 70.8 ± 8.7 kg) were matched with 9 healthy participants (42.4 ± 5.8 yr; 175.7 ± 6.7 cm; 72.1 ± 8.5 kg) who ran an official half-marathon. Before and 1-hour after the race, cardiovascular variables, sympathetic activity (catecholamines), parasympathetic (heart rate variability analysis) modulation and cardiac baroreflex function (transfer function analysis) were assessed during supine rest and a squat stand test (forced blood pressure change). RESULTS Performance time and weight loss [104.0 ± 13.2 and 111.0 ± 18.7 min; -2.57 ± 1.05 kg (-1.88 ± 0.88%) and -2.29 ± 1.15 kg (-1.59 ± 0.59%)] for healthy and T1D participants, respectively) were similar. Before running, no significant differences in any cardiovascular or autonomic variables were noted between the groups. After 1 h of recovery, both groups exhibited post-exercise hypotension, accompanied by increased sympathetic activity, decreased parasympathetic modulation, and reduced cardiac baroreflex sensitivity. CONCLUSIONS Our results showed that the pattern of change in cardiovascular and autonomic nervous activity to strenuous exercise are well maintained in T1D participants with a training history of at least 5 years.

中文翻译：

---

在训练有素的1型糖尿病和健康参与者中，对半程马拉松的心血管和自主神经反应相似。

目的该现场实验研究了经过训练的患有1型糖尿病（T1D）的人与健康人相比在21公里的跑步比赛后是否具有相似的心血管和压力反射改变。方法九名T1D（39.0±11.1 yr; 175.0±10.2 cm; 70.8±8.7 kg）与9名健康参与者（42.4±5.8 yr; 175.7±6.7 cm; 72.1±8.5 kg）进行了正式的半程马拉松比赛。赛前和赛后1小时，在仰卧休息和下蹲试验（强迫血压变化）中评估了心血管变量，交感神经活动（儿茶酚胺），副交感神经（心率变异性分析）调节和心脏压力反射功能（传递功能分析） ）。结果表演时间和体重减轻[104.0±13.2和111.0±18.7分钟；-2.57±1.05公斤（-1.88±0.88％）和-2.29±1.15公斤（-1.59±0。59％）]的健康参与者和T1D参与者）相似。跑步前，两组之间在心血管或自主神经方面无明显差异。恢复1小时后，两组均表现出运动后低血压，伴有交感神经活动增加，副交感神经调节降低和心脏压力反射敏感性降低。结论我们的结果表明，具有至少5年培训历史的T1D参与者可以很好地保持心血管和自主神经活动向剧烈运动的转变。伴有交感神经活动增加，副交感神经调节降低和心脏压力反射敏感性降低。结论我们的结果表明，具有至少5年培训历史的T1D参与者可以很好地保持心血管和自主神经活动向剧烈运动的转变。伴有交感神经活动增加，副交感神经调节降低和心脏压力反射敏感性降低。结论我们的结果表明，具有至少5年培训历史的T1D参与者可以很好地保持心血管和自主神经活动向剧烈运动的转变。