Abstract Experiments were performed for the synthesis of meso-substituted tetraphenyl porphyrins in order to obtain growth active points for PAMAM branches and a functionalized periphery with thiazole groups for increasing the metal complexation activity. Characterization by 1 H and 13 C NMR, mass spectrometry and infrared spectrometry confirmed the produced dendrimeric nanostructures; the chemical reduction of metallic Ag and Cu inside the dendrimer was proved by XPS. Finally, the toxicity of the metal-dendrimer complex was analyzed by means of the bacterial respiration test.

中文翻译：

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以卟啉为核心和功能化外围作为金属复合材料模板的PAMAM树枝状聚合物的合成及其毒性评价

摘要 为了获得 PAMAM 分支的生长活性点和具有噻唑基团的功能化外围以增加金属络合活性，进行了合成介位取代的四苯基卟啉的实验。1 H 和 13 C NMR、质谱和红外光谱的表征证实了所产生的树枝状纳米结构；XPS 证明了树枝状聚合物中金属 Ag 和 Cu 的化学还原。最后，通过细菌呼吸试验分析了金属-树枝状大分子络合物的毒性。