Characterising absorption and health-related properties of phytochemicals extracted from Malaysian palm fruit biomass after oil extraction.,Food & Function

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Characterising absorption and health-related properties of phytochemicals extracted from Malaysian palm fruit biomass after oil extraction.
Food & Function ( IF 5.1 ) Pub Date : 2020-01-16 , DOI: 10.1039/c9fo01149h
Sophie N B Selby-Pham ₁ , Lee Fong Siow , Louise E Bennett

Affiliation

After oil extraction, palm fruit biomass contains abundant water-soluble phytochemicals (PCs) with proven bioactivity in regulating oxidative stress and inflammation (OSI). For optimal bioefficacy following oral consumption, the pharmacokinetic plasma peak (Tmax) should be bio-matched with the onset of OSI, which can be predicted from the Phytochemical Absorption Prediction (PCAP) model and methodology. Predicted absorption and potential for regulation of OSI by measures of total phenolic content, antioxidant capacity and hydrogen peroxide production capacity, were applied to characterise eight extracts from mesocarp fibre and kernel shells of oil-depleted palm fruits. Results indicated post-consumption absorption Tmax ranges of 0.5-12 h and 2-6 h for intake in liquid and solid forms, respectively, and generally high antioxidant activity of the extracts. The research supports that PC extracts of palm fruit biomass have broad potential uses for human health as dietary antioxidants in foods, supplements or functional beverages.

中文翻译：

表征石油提取后从马来西亚棕榈果生物质中提取的植物化学物质的吸收和健康相关特性。

提取油后，棕榈果生物质包含丰富的水溶性植物化学物质（PCs），其在调节氧化应激和炎症（OSI）方面具有被证明的生物活性。为了在口服后获得最佳的生物功效，应将药代动力学血浆峰值（Tmax）与OSI的发生进行生物匹配，这可以通过植物化学吸收预测（PCAP）模型和方法进行预测。通过测量总酚含量，抗氧化剂能力和过氧化氢生产能力来预测OSI的吸收和调节OSI的潜力，以表征八种提取自中果皮纤维和含油棕榈果仁壳的提取物。结果表明，液体和固体形式摄入后的吸收后吸收Tmax分别为0.5-12 h和2-6 h，提取物的抗氧化活性通常很高。该研究支持棕榈果生物量的PC提取物作为食品，补品或功能性饮料中的饮食抗氧化剂，具有广泛的潜在人类健康用途。

更新日期：2020-02-13

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