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Ependymal cells in the spinal cord as neuronal progenitors.
Current Opinion in Pharmacology ( IF 4.0 ) Pub Date : 2019-12-31 , DOI: 10.1016/j.coph.2019.11.008
Victoria Moreno-Manzano 1
Affiliation  

Ependymal cells are neural progenitors and form part of the central canal of the spinal cord. Therefore, ependymal cells could serve as a potential source of neural progenitors for regenerative medicine applications. Such applications consist of endogenous activation or exogenous transplantation, alone or in combination with pharmacological treatments, to repair spinal cord injuries. This mini review describes the main phenotypical characteristics of ependymal cells from spinal cord and the opportunities offered for spinal cord injury therapeutic application.

中文翻译:

脊髓中的室管膜细胞作为神经元祖细胞。

室管膜细胞是神经祖细胞,并形成脊髓中央管的一部分。因此,室管膜细胞可以作为再生医学应用的神经祖细胞的潜在来源。这样的应用包括单独或与药物治疗结合的内源性激活或外源性移植,以修复脊髓损伤。这篇简短的综述描述了来自脊髓的室管膜细胞的主要表型特征,以及为脊髓损伤治疗应用提供的机会。
更新日期:2019-12-31
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