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Nanostructured lipid carriers: A novel hair protective product preventing hair damage and discoloration from UV radiation and thermal treatment.
Journal of Photochemistry and Photobiology B: Biology ( IF 3.9 ) Pub Date : 2019-12-30 , DOI: 10.1016/j.jphotobiol.2019.111769
Tashatai Prasertpol 1 , Waree Tiyaboonchai 2
Affiliation  

The goal of this study was to investigate the protective effects of nanostructured lipid carriers (NLCs) and vitamin E loaded NLCs (Vit E-NLCs) on preventing hair damages and discoloration against UV radiation and thermal treatment. The NLCs and Vit E-NLCs were prepared using a high-pressure homogenization technique. At optimal conditions, they showed spherical particles with a mean particle size of ~140 nm and a polydispersity index of < 0.3. Up to 90% (w/w) vitamin E acetate incorporation efficacy was achieved. The protective efficacy of the model cream containing blank-NLCs (NLCs cream) or Vit E-NLCs (Vit E-NLCs cream) was investigated. Upon exposure to UV-light and heat, the FE-SEM images revealed that the hair treated with both NLCs creams showed a smoothness of hair surface similar to the virgin hair. In accordance with protein loss, they exhibited the least protein loss as compared to the hair treated with Vit-E cream, cream base and commercial products. The same trend was observed for the discoloration test, the hair treated with both NLCs creams demonstrated the lowest total color loss, as compared to other products. Comparing between two NLCs formulations, antioxidant Vit E-NLCs showed to promote the photoprotective effect against hair damage and discoloration slightly greater than blank NLCs, but it has no extra benefit for heat protection. Considered overall, the developed NLCs and Vit E-NLCs is a novel alternative for preventing hair damage and discoloration from daily UV and heat exposure.

中文翻译:

纳米结构脂质载体:一种新型的护发产品,可防止头发受到紫外线辐射和热处理而受损和变色。

这项研究的目的是研究纳米结构脂质载体(NLCs)和负载维生素E的NLC(Vit E-NLCs)在防止头发受损以及针对紫外线辐射和热处理引起的变色方面的保护作用。使用高压均质技术制备NLC和Vit E-NLC。在最佳条件下,它们显示出球形颗粒,平均粒径为〜140 nm,多分散指数<0.3。达到了高达90%(w / w)的乙酸维生素E掺入功效。研究了包含空白NLC(NLCs乳膏)或Vit E-NLC(Vit E-NLCs乳膏)的模型乳膏的保护功效。在暴露于紫外线和热下后,FE-SEM图像显示,用两种NLC乳霜处理过的头发均表现出与初生头发相似的光滑度。根据蛋白质流失,与用Vit-E乳霜,乳霜基质和市售产品处理过的头发相比,它们的蛋白质损失最少。对于变色测试,观察到了相同的趋势,与其他产品相比,使用两种NLC乳霜处理的头发均表现出最低的总色泽损失。在两种NLC配方之间进行比较,抗氧化剂Vit E-NLC显示出比空白NLC更高的抗头发损伤和变色的光保护作用,但对热保护没有额外的好处。总的来说,已开发的NLC和Vit E-NLC是防止头发受到损伤和防止日常紫外线和热引起的变色的新型替代品。与其他产品相比,两种NLC面霜处理的头发总色泽损失最低。在两种NLC配方之间进行比较,抗氧化剂Vit E-NLC显示出比空白NLC更高的抗头发损伤和变色的光保护作用,但对热保护没有额外的好处。总的来说,已开发的NLC和Vit E-NLC是防止头发受到损伤和防止日常紫外线和热引起的变色的新型替代品。与其他产品相比,使用两种NLC面霜处理的头发总色泽损失最低。在两种NLC配方之间进行比较,抗氧化剂Vit E-NLC显示出比空白NLC更高的抗头发损伤和变色的光保护作用,但对热保护没有额外的好处。总的来说,已开发的NLC和Vit E-NLC是防止头发受到损伤和防止日常紫外线和热引起的变色的新型替代品。
更新日期:2019-12-30
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