BACKGROUND Aspergillus fumigatus infections frequently occur after solid organ transplantation. Yet, a fungal thrombosis after liver transplantation is an exceptional finding. CASE PRESENTATION We report on a 44-year-old female with an aspergillosis after liver transplantation for autoimmune hepatitis. On postoperative day (pod) 7, seizures occurred and imaging diagnostics revealed an intracranial lesion. Anidulafungin was initiated in suspicion of mycosis and switched to voriconazole on suspicion of an Aspergillus spp. infection. Progression of the cerebral lesion prompted craniotomy (pod 48) and the aspergillosis was verified. The patient was discharged with oral voriconazole therapy. Re-admission was necessary with acute-on-chronic renal failure after a tacrolimus overdose on pod 130. The patient received a pelvic angiography due to a temperature difference in the legs. It showed a complete iliac artery thrombosis which was subsecutively surgically removed. The histopathological examination revealed an Aspergillus fumigatus conglomerate. The patient died on pod 210 due to systemic aspergillosis. CONCLUSION The acute development of focal neurologic deficits is common in patients with an aspergillosis of the brain. Nevertheless, arterial thrombosis after Aspergillus fumigatus is less frequent and, to the best of our knowledge, its occurrence after liver transplantation has not yet been reported so far. Due to its rarity, we added a review of the literature to this manuscript.

中文翻译：

---

烟气曲霉在肝移植后引起的artery动脉致死性血栓形成：病例报告和文献复习。

背景技术烟熏曲霉感染在实体器官移植后经常发生。然而，肝移植后的真菌血栓形成是一个例外的发现。病例介绍我们报道了一名44岁女性因自身免疫性肝炎肝移植后曲霉病。术后第7天（荚）发生癫痫发作，影像学诊断显示颅内病变。怀疑真菌病引发阿尼芬净，并因怀疑曲霉属而改用伏立康唑。感染。脑部病变的进展促使开颅手术（荚48），并证实了曲霉病。该患者已接受伏立康唑口服治疗。他克莫司过量服用荚果130后，急性慢性肾功能衰竭必须重新入院。由于腿部温度差异，患者接受了骨盆血管造影。它显示出完整的动脉血栓形成，这是通过外科手术切除的。组织病理学检查显示烟曲霉聚集体。该患者由于全身性曲霉病而在荚210上死亡。结论局灶性神经功能缺损的急性发展在脑曲霉病患者中很常见。然而，烟曲霉后的动脉血栓形成的频率较低，据我们所知，到目前为止，尚无肝移植后发生动脉血栓的报道。由于其稀有性，我们在此手稿中增加了文献综述。组织病理学检查显示烟曲霉聚集体。该患者由于全身性曲霉病而在荚210上死亡。结论局灶性神经功能缺损的急性发展在脑曲霉病患者中很常见。然而，烟曲霉后的动脉血栓形成的频率较低，据我们所知，到目前为止，尚无肝移植后发生动脉血栓的报道。由于其稀有性，我们在此手稿中增加了文献综述。组织病理学检查显示烟曲霉聚集体。该患者由于全身性曲霉病而在荚210上死亡。结论局灶性神经功能缺损的急性发展在脑曲霉病患者中很常见。然而，烟曲霉后的动脉血栓形成的频率较低，据我们所知，到目前为止，尚无肝移植后发生动脉血栓的报道。由于其稀有性，我们在此手稿中增加了文献综述。据我们所知，迄今尚未报道其在肝移植后发生的情况。由于其稀有性，我们在此手稿中增加了文献综述。据我们所知，迄今尚未报道其在肝移植后发生的情况。由于其稀有性，我们在此手稿中增加了文献综述。