BACKGROUND The initial management of pneumothorax remains controversial, and we speculated that this might be because there is no method available for evaluation of air leak during initial management. We have developed a system for measurement of intrapleural pressure in pneumothorax to address air leak without the need for chest drainage. The aim of this clinical study was to confirm the ability of this measurement system and to determine the clinical impact of management of air leak. METHODS Patients in whom need aspiration was indicated for spontaneous pneumothorax were enrolled in the study. The intrapleural pressure was measured during stable breathing and data recorded when patients were coughing were excluded. RESULTS Eleven patients were enrolled in the study between December 2016 to July 2017. The patterns in change of intrapleural pressure varied widely depending on the state of the pneumothorax. The mean intrapleural pressure values on end-inspiration and end-expiration in patients with persistent air leak was significantly lower than those in patients without persistent air leak (p = 0.020). The number of negative mean pressure recordings in end-inspiration and end-expiration was significantly lower in patients with persistent air leak than in those without persistent air leak (p = 0.0060). CONCLUSIONS In this study, we demonstrated that intrapleural pressure could be successfully measured and visualized in patients with pneumothorax. Whether or not the pressure value is a predictor of persistent air leak needs to be confirmed in the future.

中文翻译：

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自发性气胸患者胸膜内压力的测量：一项初步研究。

背景技术气胸的初始治疗仍存在争议，我们推测这可能是因为在初始治疗期间尚无评估气漏的方法。我们开发了一种无需胸腔引流即可测量气胸胸膜内压力的系统，以解决漏气问题。这项临床研究的目的是确认该测量系统的功能并确定漏气管理的临床影响。方法纳入需要抽吸的自发性气胸患者。在稳定呼吸期间测量胸膜内压力，并且排除患者咳嗽时记录的数据。结果2016年12月至2017年7月期间招募了11名患者。胸膜内压力变化的模式根据气胸的状态而变化很大。持续漏气的患者的最终胸膜内压力值在吸气和呼气末显着低于没有持续漏气的患者（p = 0.020）。持续漏气的患者的终末吸气和呼气末负平均压力记录数显着低于无持续漏气的患者（p = 0.0060）。结论在这项研究中，我们证明了气胸患者可以成功地测量并可视化胸膜内压力。将来是否需要确定压力值是否是持续漏气的指标。持续性漏气的患者的胸腔内平均压力值在呼气和呼气末显着低于无持续性漏气的患者（p = 0.020）。持续漏气的患者的终末吸气和呼气末负平均压力记录数显着低于无持续漏气的患者（p = 0.0060）。结论在这项研究中，我们证明了气胸患者可以成功地测量并可视化胸膜内压力。将来是否需要确定压力值是否是持续漏气的指标。持续漏气的患者的最终胸膜内压力值在吸气和呼气末显着低于没有持续漏气的患者（p = 0.020）。持续漏气的患者的终末吸气和呼气末负平均压力记录数显着低于无持续漏气的患者（p = 0.0060）。结论在这项研究中，我们证明了气胸患者可以成功地测量并可视化胸膜内压力。将来是否需要确定压力值是否是持续漏气的指标。持续漏气的患者的终末吸气和呼气末负平均压力记录数显着低于无持续漏气的患者（p = 0.0060）。结论在这项研究中，我们证明了气胸患者可以成功地测量并可视化胸膜内压力。将来是否需要确定压力值是否是持续漏气的指标。持续漏气的患者的终末吸气和呼气末负平均压力记录数显着低于无持续漏气的患者（p = 0.0060）。结论在这项研究中，我们证明了气胸患者可以成功地测量并可视化胸膜内压力。将来是否需要确定压力值是否是持续漏气的指标。