BACKGROUND Gastrointestinal stromal tumors (GISTs) at the esophagogastric junction are rare and its treatment is complicated and challenging. Endoscopic resection has advantages with less complications compared to open and laparoscopic surgery. CASE PRESENTATION We report a 33-year-old male patient who was admitted to our department complaining of abdominal fullness for 20 days. A huge submucosal tumor at the esophagogastric junction was found by upper gastrointestinal endoscopy. We successfully resected the lesion through endoscopic submucosal excavation without complications, which was pathologically confirmed to be a GIST. The patient was discharged 5 days after operation and has been doing well, and there was no recurrence 8 months after the operation. CONCLUSION ESE is possibly an effective and minimally invasive method of giant esophagogastric junction stromal tumor.

中文翻译：

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食管胃交界处巨大胃肠道间质瘤的内镜切除术：病例报告。

背景技术食管胃交界处的胃肠道间质瘤（GIST）很少见，其治疗复杂且具有挑战性。与开放和腹腔镜手术相比，内窥镜切除术具有并发症少的优势。病例介绍我们报告了一名33岁的男性患者，他被收治到我们的科室，​​抱怨腹部饱满20天。上消化道内窥镜检查发现食管胃交界处有巨大的粘膜下肿瘤。我们通过内窥镜黏膜下切除术成功切除了病灶，没有发生并发症，这在病理学上被确认为是GIST。病人在手术后5天出院，并且情况良好，并且在手术后8个月没有复发。