Magnesium alloy (MgA) has been extensively used as orthopedic and cardiovascular scaffolds in virtue of its good biocompatibility, unique biodegradability and excellent mechanical properties. However, poor corrosion resistance and easy infection after implantation seriously limit the potential applications of MgA in the biomedical field. Herein, we fabricated bilayered nanoarrays of hydroxyapatite nanorods (HANRs) and ZnO nanorods (ZnONRs) onto the surface of MgA (MgA-MgO-HANRs-ZnONRs) via micro-arc oxidation (MAO) treatment, microwave-assisted hydrothermal and hydrothermal methods. The morphology and chemical composition of MgA-MgO-HANRs-ZnONRs was characterized by FE-SEM, XRD and EDS, indicating that HANRs-ZnONRs bilayered nanoarrays were fabricated on the surface of MgA-MgO. The surface of MgA-MgO-HANRs-ZnONRs exhibited excellent hydrophilicity as evidenced by the low water contact angle of 3°. Compared with the original MgA, the corrosion resistance of MgA-MgO-HANRs-ZnONRs was obviously improved with decreasing the corrosive current density (i_corr) of 2 orders of magnitude. The MgA-MgO-HANRs-ZnONRs performed excellent antibacterial properties with the bactericidal rate of 96.5% against S. aureus and 94.3% against E. coli.

镁合金（MgA）具有良好的生物相容性，独特的生物降解性和出色的机械性能，已被广泛用作骨科和心血管支架。然而，差的耐腐蚀性和植入后易于感染严重地限制了MgA在生物医学领域的潜在应用。在这里，我们通过微弧氧化（MAO）处理，微波辅助水热法和水热法将羟基磷灰石纳米棒（HANRs）和ZnO纳米棒（ZnONRs）的双层纳米阵列制造到MgA（MgA-MgO-HANRs-ZnONRs）的表面上。用FE-SEM，XRD和EDS对MgA-MgO-HANRs-ZnONRs的形貌和化学组成进行了表征，表明在MgA-MgO表面制备了HANRs-ZnONRs双层纳米阵列。MgA-MgO-HANRs-ZnONRs的表面表现出优异的亲水性，这是由3°的低水接触角所证明的。与原始MgA相比，MgA-MgO-HANRs-ZnONRs的耐蚀性随着腐蚀电流密度的降低而明显提高（i _corr）为2个数量级。MgA-MgO-HANRs-ZnONRs具有优异的抗菌性能，对金黄色葡萄球菌的杀菌率为96.5％，对大肠杆菌的杀菌率为94.3％。