BACKGROUND To evaluate the efficacy of microvascular decompression (MVD) in reducing hypertension (HTN) in hypertensive patients with trigeminal neuralgia (TN). METHODS The clinical data of 58 cases of neurogenic HTN with TN treated in our hospital were retrospectively reviewed. Preoperative MR revealed abnormal blood pressure in the left rostral ventrolateral medulla (RVLM) and the posterior cranial nerve root entry zone (REZ). The patients were divided into control group: only trigeminal nerve was treated with MVD; experimental group: trigeminal nerve, RVLM and REZ were treated with MVD at the same time. The patients were followed up for 6 months to 1 year to observe the changes of blood pressure. RESULTS There was no significant difference in gender, age, course of TN, course of HTN, grade of HTN and preoperative blood pressure between the two groups. After operation, the effective rate of HTN improvement with MVD was 32.1% in the control group. There was no significant difference in the preoperative and post operative blood pressure. (P△SBP = 0.131; P△BDP = 0.078). In the experimental group, the effective rate was 83.3%. The postoperative blood pressure was significantly lower than preoperative values. (P△SBP < 0.001; P△DBP < 0.001). CONCLUSIONS MVD is an effective treatment for neurogenic HTN. However, the criteria for selecting hypertensive patients who need MVD to control their HTN still needs to be further determined. Possible indications may include: left trigeminal neuralgia, neurogenic HTN; abnormal blood pressure compression in the left RVLM and REZ areas on MR; and blood pressure in these patients can not be effectively controlled by drugs.

中文翻译：

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微血管减压治疗三叉神经痛神经源性高血压。

背景技术为了评估三叉神经痛（TN）高血压患者微血管减压（MVD）降低高血压（HTN）的功效。方法回顾性分析我院收治的58例神经源性TNN性TNN的临床资料。术前MR显示左延髓腹侧延髓（RVLM）和颅后神经根进入区（REZ）血压异常。将患者分为对照组：仅用MVD治疗三叉神经；用MVD治疗。实验组：三叉神经，RVLM和REZ同时用MVD治疗。随访6个月至1年，观察血压的变化。结果性别，年龄，TN病程，HTN病程，两组之间的HTN等级和术前血压。术后，对照组MVD改善HTN的有效率为32.1％。术前和术后血压无明显差异。（P△SBP ＝ 0.131； P△BDP ＝ 0.078）。实验组有效率83.3％。术后血压明显低于术前值。（P△SBP ＜0.001； P△DBP ＜0.001）。结论MVD是治疗神经源性HTN的有效方法。但是，仍然需要进一步确定选择需要MVD来控制其HTN的高血压患者的标准。可能的适应症可能包括：左三叉神经痛，神经源性HTN；MR的左RVLM和REZ区域的血压异常压缩；