BACKGROUND Patellar tendinopathy is an extremely debilitating condition and its treatment usually requires a combination of clinical approaches. Therapeutic ultrasound (TUS) is one of the most available electrophysical agent in rehabilitation settings; however, there is also a lack of high-quality studies that test different dosimetric aspects of TUS. Thus, the purpose of this study is to evaluate the short-, medium-, and long-term effects of the combination of high-energy TUS with a rehabilitation program for patellar tendinopathy. METHODS This will be a randomized, placebo-controlled trial with blinding of patients, assessors, and therapist. The setting is an outpatient physical therapy clinic. We will recruit 66 participants (male and female) aged between 18 and 40 years and presenting with patellar tendinopathy. A treatment combining high-energy dose TUS and a rehabilitation program for patellar tendinopathy will be delivered twice a week for 8 weeks. The control group will receive the same treatment, but with a placebo TUS. The effectiveness of the intervention will be measured at the beginning (baseline), midpoint (4 weeks), and end of treatment (8 weeks), as well as at 3- and 6-months post-treatment. Primary outcomes will be pain intensity (visual analogue scale, VAS), and VISA-P questionnaire and primary time points will be baseline (T0) and the end of the program (T2). Also, IPAQ-short form questionnaire, muscle strength (manual dynamometry), 2D kinematics, pain pressure threshold (PPT) algometry, thermography, and magnetic resonance imaging (MRI) will be collected. DISCUSSION TUS will be applied in an attempt to enhance the results obtained with the rehabilitation program proposed in this study, as well as stimulate some repair responses in individuals undergoing treatment for patellar tendinopathy, which in turn may optimize and improve treatment programs for patellar tendinopathy as well as to establish new guidelines for the application of TUS. TRIAL REGISTRATION This study was prospectively registered at April-3rd-2018 and updated at September-1st-2019 in the Brazilian Registry of Clinical Trials (REBEC) under the registration number: RBR-658n6w.

中文翻译：

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高能量剂量的治疗性超声波治疗pa骨肌腱病：随机安慰剂对照临床试验的方案。

背景技术Pat骨肌腱病是一种极度衰弱的疾病，其治疗通常需要临床方法的结合。治疗性超声波（TUS）是康复环境中最可用的电物理试剂之一；但是，也缺乏用于测试TUS不同剂量方面的高质量研究。因此，本研究的目的是评估高能量TUS与pa骨肌腱病康复计划相结合的短期，中期和长期效果。方法这将是一项随机，安慰剂对照的试验，对患者，评估者和治疗师致盲。该场所是门诊物理治疗诊所。我们将招募66名年龄在18至40岁之间并伴有pa骨肌腱病的参与者（男性和女性）。高能剂量TUS和and骨肌腱病康复计划相结合的治疗将每周两次，共8周。对照组将接受相同的治疗，但使用安慰剂TUS。干预的有效性将在治疗的开始（基线），中点（4周）和治疗结束（8周）以及治疗后3个月和6个月进行评估。主要结果将是疼痛强度（视觉模拟量表，VAS）和VISA-P问卷，主要时间点将是基线（T0）和计划结束（T2）。此外，还将收集IPAQ简短问卷，肌肉力量（手动测功），2D运动学，疼痛压力阈值（PPT）立体测量法，热成像和磁共振成像（MRI）。讨论TUS将用于尝试增强通过本研究提出的康复计划获得的结果，并刺激接受pa骨肌腱病治疗的个体的某些修复反应，从而可以优化和改善as骨肌腱病的治疗方案，如以及建立TUS应用的新指南。试验注册本研究预期于2018年4月3日注册，并于2019年9月1日在巴西临床试验注册中心（REBEC）更新，注册号为：RBR-658n6w。进而可以优化和改善pa肌腱病的治疗方案，并为TUS的应用建立新的指南。试验注册本研究预期于2018年4月3日注册，并于2019年9月1日在巴西临床试验注册中心（REBEC）更新，注册号为：RBR-658n6w。进而可以优化和改善pa肌腱病的治疗方案，并为TUS的应用建立新的指南。试验注册本研究预期于2018年4月3日注册，并于2019年9月1日在巴西临床试验注册中心（REBEC）更新，注册号为：RBR-658n6w。