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Effect of multipurpose care solutions upon physical dimensions of silicone hydrogel contact lenses.
Journal of Biomedical Materials Research Part B: Applied Biomaterials ( IF 3.2 ) Pub Date : 2019-12-26 , DOI: 10.1002/jbm.b.34533
Stephanie M Smith 1, 2 , Dongkai Zhu 1, 2 , David Pierre 1, 2 , Jeremy L Gilbert 1, 2 , Joseph A Chinn 3
Affiliation  

Interactions between contact lens multipurpose solution (MPS) components and the contact lenses with which they are used are both lens and solution dependent. As such, lens dimensional changes may arise after cleaning and immersion cycling in different lens care solutions over different time courses. In this study, the dimensional stability of five planned‐replacement silicone hydrogel lenses (lotrafilcon B, comfilcon A, senofilcon A, senofilcon C, and samfilcon A) over 30 cycles in three different MPSs (Biotrue, OPTI‐FREE Express, and OPTI‐FREE Puremoist) was evaluated. Measurements of diameter, sagittal depth, power, roundness, and center thickness were obtained prior to, during, and after 30 cycles of cleaning and storage. Diameters of all lenses increased when soaked in Express or Biotrue but held the International Standards Organization (ISO) tolerance over the full course of 30 disinfection cycles; however, the diameters of comfilcon A, senofilcon A, senofilcon C, and samfilcon A lenses soaked in Puremoist exceeded ISO tolerance after between 4 and 9 immersion cycles. In contrast, the diameter of lotrafilcon B held tolerance. Similarly, all lenses cycled in Express or Biotrue held tolerance for sagittal depth, while in Puremoist only lotrafilcon B held tolerance. All lenses became less round in all MPSs but held tolerance for both power and central thickness. Given the lack of reported clinical issues with Puremoist when used with lenses other than lotrafilcon B, we propose that it may be appropriate to revisit the ISO test methods and tolerances to determine if they are still applicable for silicone hydrogel lenses.

中文翻译:

多用途护理液对硅水凝胶隐形眼镜物理尺寸的影响。

隐形眼镜多用途溶液 (MPS) 组件与使用它们的隐形眼镜之间的相互作用取决于镜片和溶液。因此,在不同的时间过程中,在不同的镜片护理液中清洗和浸泡循环后,镜片尺寸可能会发生变化。在这项研究中,五种计划更换硅水凝胶镜片(lotrafilcon B、comfilcon A、senofilcon A、senofilcon C 和 samfilcon A)在三种不同的 MPS(Biotrue、OPTI-FREE Express 和 OPTI-免费 Puremoist) 进行了评估。在 30 次清洁和储存循环之前、期间和之后获得直径、矢状深度、功率、圆度和中心厚度的测量值。浸泡在 Express 或 Biotrue 中后,所有镜片的直径都会增加,但在 30 个消毒周期的整个过程中保持国际标准组织 (ISO) 的耐受性;然而,浸泡在 Puremoist 中的 comfilcon A、senofilcon A、senofilcon C 和 samfilcon A 镜片的直径在 4 到 9 次浸泡循环后超过了 ISO 公差。相比之下,lotrafilcon B 的直径保持公差。同样,在 Express 或 Biotrue 中循环使用的所有镜片都具有矢状深度的容差,而在 Puremoist 中,只有 lotrafilcon B 具有容差。在所有 MPS 中,所有镜片都变得不那么圆,但对焦度和中心厚度都保持公差。鉴于在与 Lotrafilcon B 以外的镜片一起使用时,没有报告 Puremoist 的临床问题,
更新日期:2019-12-26
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