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Visible-light-promoted CN and CS bonds formation: A catalyst and solvent-free photochemical approach for the synthesis of 1,3-thiazolidin-4-ones
Journal of Photochemistry and Photobiology A: Chemistry ( IF 4.1 ) Pub Date : 2019-12-27 , DOI: 10.1016/j.jphotochem.2019.112347
Mohd Nazeef , Km Neha Shivhare , Shabir Ali , Khursheed Ansari , Mohd Danish Ansari , Saurabh K. Tiwari , Vikas Yadav , I.R. Siddiqui

A visible-light-induced, one-pot mild and efficient, multicomponent-tandem synthesis of diversified 1,3-thiazolidin-4-ones under catalyst and solvent-free conditions is reported. Here, visible-light, an ideal source of energy, has been used as photochemical activator to generate Csingle bondN and Csingle bondS bonds under radical mechanistic pathway from aromatic amines, aldehydes and thioglycolic acid. The reported methodology can be extensively utilized to explore 1,3-thiazolidin-4-one derivatives with high selectivity, short reaction time, tolerance of functional groups, cost effectiveness and excellent yields.



中文翻译:

可见光促进的C 单键N和C 单键S键形成:合成1,3-噻唑烷酮-4-酮的催化剂和无溶剂光化学方法

据报道,在无催化剂和无溶剂的条件下,可见光诱导的一锅式温和高效的多组分串联合成了多种1,3-噻唑烷酮-4-酮。在这里,可见光是一种理想的能源,已被用作光化学活化剂,通过自由基机制从芳族胺,醛和巯基乙酸生成C 单键N和C 单键S键。所报道的方法可以广泛地用于探索具有高选择性,短反应时间,对官能团的耐受性,成本效益和优异收率的1,3-噻唑烷丁-4-酮衍生物。

更新日期:2019-12-27
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