Abstract Parylene C films have numerous advantages. The versatility of parylene C coatings makes them useful in a broad range of biomedical applications. The coatings are widely used commercially because of the unique combination of their physicochemical properties, i.e. flexibility and dielectricity. The chemical vapour deposition process enables parylene C conformal coatings to be applied to even the most complex medical devices. The coatings can be customised for the desired application using surface modification methods, which alter surface chemistry and topography. In this review, we summarise the last ten years (2008–2018) of research on parylene C for biomedical applications. We discuss how parylene C properties can be modulated through surface and bulk modifications to improve its key functions, i.e. anticorrosive, biocompatible, anti-infection, and therapeutic functions. We emphasise current and potential biomedical applications and finally highlight the advantages and limitations of the coatings, pointing out the perspectives and the most promising research trends.

中文翻译：

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用于生物医学应用的聚对二甲苯 C 聚合物的最新进展：综述

摘要 Parylene C 薄膜具有许多优点。聚对二甲苯 C 涂层的多功能性使其可用于广泛的生物医学应用。由于其物理化学特性（即柔韧性和介电性）的独特组合，该涂层在商业上得到广泛应用。化学气相沉积工艺使聚对二甲苯 C 保形涂层能够应用于最复杂的医疗设备。可以使用改变表面化学和形貌的表面改性方法为所需应用定制涂层。在这篇综述中，我们总结了过去十年（2008-2018）用于生物医学应用的聚对二甲苯 C 的研究。我们讨论了如何通过表面和本体改性来调节聚对二甲苯 C 的特性以改善其关键功能，即防腐、生物相容性、抗感染和治疗功能。我们强调当前和潜在的生物医学应用，最后强调涂层的优势和局限性，指出前景和最有前途的研究趋势。