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Conjunctivitis in patients with atopic dermatitis treated with dupilumab is associated with higher baseline serum levels of immunoglobulin E and thymus and activation-regulated chemokine but not clinical severity in a real-world setting.
Journal of the American Academy of Dermatology ( IF 12.8 ) Pub Date : 2019-12-26 , DOI: 10.1016/j.jaad.2019.12.039
Hideaki Uchida 1 , Masahiro Kamata 1 , Mayumi Nagata 1 , Saki Fukaya 1 , Kotaro Hayashi 1 , Atsuko Fukuyasu 1 , Takamitsu Tanaka 1 , Takeko Ishikawa 1 , Takamitsu Ohnishi 1 , Yayoi Tada 1
Affiliation  

Conjunctivitis in patients with atopic dermatitis treated with dupilumab is associated with baseline serum levels of IgE and TARC but not subjective severity scores in a real-world setting. These objective parameters are useful as practical predictors of later development of conjunctivitis.



中文翻译:

用dupilumab治疗的特应性皮炎患者的结膜炎与免疫球蛋白E和胸腺的基线血清水平较高以及活化调节的趋化因子有关,但在现实环境中与临床严重程度无关。

用dupilumab治疗的特应性皮炎患者的结膜炎与血清IgE和TARC的基线水平相关,但与真实环境中的主观严重度评分无关。这些客观参数可用作结膜炎以后发展的实际预测指标。

更新日期:2019-12-27
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