OBJECTIVE This study systematically reviews the literature on self-healing microcapsule technology and evaluates the biocompatibility of self-healing microcapsules and the efficiency of crack repair within resin-based dental composites. METHODS An electronic search was carried out using the following databases: MedLine (PubMed), Embase, the Cochrane Library and Google Scholar. All titles and abstracts of the articles and patents found were analysed and selected according to the eligibility criteria. Only studies published in English were included; the outcomes sought for this review were dental resin composites with self-healing potential. There were no restrictions on the type of self-healing system involved in dental resin composites. RESULTS The search yielded 10 studies and 2 patents involving self-healing approaches to dental resin composites. According to the current literature on self-healing dental resin composites, when a crack or damage occurs to the composite, microcapsules rupture, releasing the healing agent to repair the crack with a self-healing performance ranging from 25% to 80% of the virgin fracture toughness. SIGNIFICANCE Self-healing strategies used with resin composite materials have, to date, been bioinspired. So far, self-healing microcapsule systems within dental composites include poly urea-formaldehyde (PUF) or silica microcapsules. The main healing agents used in PUF microcapsules are DCPD monomer and TEGDMA-DHEPT, with other agents also explored. Silica microcapsules use water/polyacid as a healing agent. All self-healing systems have shown promising results for self-repair and crack inhibition, suggesting a prolonged life of dental composite restorations. More investigations and mechanical enhancements should be directed toward self-healing technologies in dental resin composites.

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基于自主自愈微胶囊的牙科树脂复合材料的综述和现状。

目的 本研究系统回顾了有关自愈微胶囊技术的文献，评估了自愈微胶囊的生物相容性和树脂基牙科复合材料的裂缝修复效率。方法 使用以下数据库进行电子搜索：MedLine (PubMed)、Embase、Cochrane Library 和 Google Scholar。根据资格标准对发现的文章和专利的所有标题和摘要进行分析和选择。仅包括以英文发表的研究；本次审查寻求的结果是具有自愈潜力的牙科树脂复合材料。牙科树脂复合材料中涉及的自愈系统的类型没有限制。结果 检索产生了 10 项研究和 2 项专利，涉及牙科树脂复合材料的自修复方法。根据目前关于自修复牙科树脂复合材料的文献，当复合材料出现裂纹或损伤时，微囊破裂，释放出愈合剂修复裂纹，自修复性能为原始材料的25%~80%。断裂韧性。意义 迄今为止，用于树脂复合材料的自我修复策略受到了生物启发。到目前为止，牙科复合材料中的自愈微胶囊系统包括聚脲甲醛 (PUF) 或二氧化硅微胶囊。PUF 微胶囊中使用的主要愈合剂是 DCPD 单体和 TEGDMA-DHEPT，还探索了其他药物。二氧化硅微胶囊使用水/多元酸作为愈合剂。所有自修复系统在自修复和裂纹抑制方面都显示出有希望的结果，这表明牙科复合材料修复体的使用寿命更长。更多的研究和机械改进应针对牙科树脂复合材料的自愈技术。