Recent advances in 3D printing have provided unprecedented opportunities in bone tissue engineering applications for producing a variety of complex patient-specific implants for the treatment of critical-sized bone defects. Natural medicinal compounds (NMCs) with osteogenic potential can be incorporated into these 3D-printed parts to improve bone formation and therefore enhance implant performance. Using NMCs to treat bone-related disorders may prove to be a healthy preventive choice as they are considered safe, have lesser or no side effects, and are more suitable for prolonged use than synthetic drugs. In this review paper, the current challenges of bone tissue engineering are addressed briefly, highlighting the immense potential of NMCs integrated within tissue engineering scaffolds for orthopedic and dental applications.

中文翻译：

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骨组织工程中的天然药用化合物。


3D 打印的最新进展为骨组织工程应用提供了前所未有的机会，可生产各种复杂的患者专用植入物，用于治疗临界尺寸的骨缺损。具有成骨潜力的天然药用化合物 (NMC) 可以融入这些 3D 打印部件中，以改善骨形成，从而提高植入物的性能。使用 NMC 治疗骨相关疾病可能被证明是一种健康的预防选择，因为它们被认为是安全的，副作用较小或没有副作用，并且比合成药物更适合长期使用。在这篇综述论文中，简要讨论了骨组织工程当前面临的挑战，强调了将 NMC 集成到组织工程支架中用于骨科和牙科应用的巨大潜力。