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Relationship Between Olfactory Disturbance After Acute Ischemic Stroke and Latent Thalamic Hypoperfusion.
Chemical Senses ( IF 2.8 ) Pub Date : 2019-12-24 , DOI: 10.1093/chemse/bjz077
Kazuhiro Okamoto 1 , Hideaki Shiga 2 , Hisako Nakamura 3 , Makoto Matsui 4 , Takaki Miwa 2
Affiliation  

Odor detection, recognition and identification were assessed in 19 acute ischemic stroke patients who had no MRI-detectable thalamic lesions but in whom technetium-99m ethyl cysteinate dimer single photon emission tomography revealed thalamic hypoperfusion. Although these patients were unaware of reduced olfactory function, they exhibited significantly lower scores in tests for odor identification and recognition threshold as compared to 9 ischemic stroke controls that had normal thalamic hypoperfusion. However, absolute odor detection thresholds were similar in the two groups. These results demonstrate the usefulness of cerebral perfusion scintigraphy in assessing sensory loss after ischemic stroke and provide further evidence for the role of the thalamus in olfaction.

中文翻译:

急性缺血性中风后嗅觉障碍与潜在丘脑灌注不足之间的关系。

气味检测,识别和鉴定评估了19例急性缺血性脑卒中患者,这些患者没有MRI可检测到的丘脑损害,但99m的半胱氨酸乙酯二聚体单光子发射断层显像显示丘脑灌注不足。尽管这些患者没有意识到嗅觉功能降低,但是与9个丘脑灌注不足的缺血性卒中对照相比,他们在气味识别和识别阈值测试中的得分明显较低。但是,两组的绝对气味检测阈值相似。这些结果证明了脑灌注显像在评估缺血性中风后的感觉丧失方面的有用性,并为丘脑在嗅觉中的作用提供了进一步的证据。
更新日期:2020-04-17
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