Abstract In this work, we present an Atmospheric Pressure Chemical Ionisation (APCI) study of several organic solvents relevant to Thin Layer Chromatography (TLC) (methanol, ethanol, propan-2-ol, acetone, ethyl acetate, diethylamine). The solvents were investigated using an Ion Mobility Spectrometry (IMS) combined with orthogonal acceleration Time Of Flight Mass Spectrometry (IMS-oaTOF MS). The solvents were iononised by Reactant Ions (RI – H+.(H2O)3,4 m/z 55 and 73). The ions were analysed using IMS and IMS-oaTOF technique was used to assign the ion mobility peaks to ions according to their m/z. IMS spectra of methanol, ethanol, propan-2-ol and diethylamine exhibited only one peak (reduced ion mobilities of 2.19, 2.07, 1.98, 2.06 cm2s−1V−1 respectively) whereas acetone and ethyl acetate were characterised by two peaks (2.15, 1.85 and 1.94, 1.53 cm2s−1V−1 respectively). The IMS-oaTOF spectrometry assigned IMS peaks of VOCs to M⋅H+(H2O)n. n = 0,1,2 or M2⋅H+ ions, where M represents the solvent molecule.

中文翻译：

---

通过离子迁移谱结合正交加速飞行时间质谱对选定的挥发性有机化合物 (VOC) 进行大气压化学电离研究

摘要 在这项工作中，我们对与薄层色谱 (TLC) 相关的几种有机溶剂（甲醇、乙醇、2-丙醇、丙酮、乙酸乙酯、二乙胺）进行了大气压化学电离 (APCI) 研究。使用离子迁移谱 (IMS) 结合正交加速飞行时间质谱 (IMS-oaTOF MS) 研究溶剂。溶剂被反应离子（RI – H+.(H2O)3,4 m/z 55 和 73）电离。使用 IMS 分析离子，并使用 IMS-oaTOF 技术根据离子的 m/z 将离子迁移率峰分配给离子。甲醇、乙醇、2-丙醇和二乙胺的 IMS 谱图仅显示一个峰（降低的离子迁移率分别为 2.19、2.07、1.98、2.06 cm2s-1V-1），而丙酮和乙酸乙酯则有两个峰（2.15 1.85 和 1.94，1。53 cm2s−1V−1）。IMS-oaTOF 光谱法将 VOC 的 IMS 峰分配给 M⋅H+(H2O)n。n = 0,1,2 或 M2⋅H+ 离子，其中 M 代表溶剂分子。