The synthesis method of a zinc-tantalum catalyst supported on three-dimensional mesoporous silica with high specific surface area was studied. Its activity in the conversion of ethanol to butadiene was optimized using the Design of Experiment approach. A Plackett-Burman screening design identified the important preparation parameters, notably the ratio of Zn to Ta. It was subsequently optimized using the Response Surface Methodology, affording a highly active catalyst.

中文翻译：

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使用实验设计方法改进Lebedev工艺的Zn-Ta-TUD-1的合成

研究了高比表面积三维介孔二氧化硅负载的锌钽催化剂的合成方法。使用实验设计方法优化了其在乙醇转化为丁二烯中的活性。Plackett-Burman筛选设计确定了重要的制备参数，尤其是Zn与Ta的比例。随后使用响应表面方法进行了优化，提供了高活性催化剂。