Evidence for contamination with C. trachomatis in the household environment of children with active Trachoma: A cross-sectional study in Kongwa, Tanzania.,PLOS Neglected Tropical Diseases

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Evidence for contamination with C. trachomatis in the household environment of children with active Trachoma: A cross-sectional study in Kongwa, Tanzania.
PLOS Neglected Tropical Diseases ( IF 3.4 ) Pub Date : 2019-12-23 , DOI: 10.1371/journal.pntd.0007834
Sheila K West ₁ , Afshan A Nanji ₁ , Harran Mkocha ₂ , Beatriz Munoz ₁ , Charlotte Gaydos ₃ , Thomas C Quinn _{3,

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Affiliation

BACKGROUND Trachoma, a conjunctivitis caused by repeated infections with Chlamydia trachomatis, remains a significant cause of blindness worldwide. While mass treatments with azithromycin decreases disease and infection, re-emergence occurs, indicating that elimination may require other sustainable interventions. Environmental changes largely focus on facial hygiene and latrines, but further work to identify other possible transmission targets are needed. We sought to determine, in a cross-sectional survey of households of children with active trachoma, if we could detect the presence of Chlamydia trachomatis on household objects and on family members based on sleeping and caretaking patterns. METHODS In five villages in Kongwa, Tanzania, children

中文翻译：

活动性沙眼儿童家庭环境中沙眼衣原体污染的证据：坦桑尼亚Kongwa的横断面研究。

背景技术沙眼是由沙眼衣原体的反复感染引起的结膜炎，仍然是全世界失明的重要原因。虽然阿奇霉素的大规模治疗可减少疾病和感染，但会再次出现，表明消除可能需要其他可持续的干预措施。环境变化主要集中在面部卫生和厕所上，但是需要进一步的工作来确定其他可能的传播目标。我们试图通过对患有活动性沙眼的儿童的家庭进行的横断面调查，确定我们是否可以根据睡眠和照护方式来检测家庭对象和家庭成员中是否存在沙眼衣原体。方法在坦桑尼亚康瓦的五个村庄中，孩子们

更新日期：2019-12-25

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