当前位置: X-MOL 学术Nat. Rev. Immunol. › 论文详情
Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)
bnAbs for HIV: shepherding towards improbable mutations.
Nature Reviews Immunology ( IF 67.7 ) Pub Date : 2020-02-01 , DOI: 10.1038/s41577-019-0270-0
Alexandra Flemming 1
Affiliation  

The design of vaccines that induce broadly neutralizing antibodies (bnAbs) to HIV is extremely challenging. Two reports now demonstrate strategies for the design of immunogens that can induce the production of bnAb precursors and guide these towards the acquisition of improbable mutations.

中文翻译:

艾滋病毒的bnAb:转向难以​​置信的突变。

诱导HIV广泛中和抗体(bnAbs)的疫苗设计极具挑战性。现在有两份报告证明了设计免疫原的策略,可以诱导bnAb前体的产生,并指导这些方法获得不可能的突变。
更新日期:2019-12-25
down
wechat
bug