BACKGROUND Relative to their application with adults there is currently little information about the application of preference-based health-related quality of life (HRQL) instruments among populations of young people. The Child Health Utility 9D (CHU9D) is a paediatric-specific generic preference-based HRQL instrument, recently translated and linguistically validated into Danish (CHU9D-DK). The purpose of this study was to investigate the construct validity of the CHU9D-DK in a sample of Danish high school students. METHODS All students attending a Danish High School were invited to participate in a web-based survey in January 2018 (N = 272). The survey included the CHU9D-DK, the young adult version of the Pediatric Quality of Life Inventory™ 4.0 Generic Core Scales (PedsQL), self-reported health status, presence/absence of disability/chronic diseases, life satisfaction, and socio-economic questions. CHU9D-DK utility scores were generated by employing the two scoring algorithms developed from adults in the UK and adolescents in Australia, respectively. Internal consistency, reliability and construct validity of the CHU9D-DK instrument were investigated. RESULTS Two hundred and twenty-eight (84%) students consented to participate and completed the survey. The mean ± (standard deviation) values of the CHU9D-DK utilities were 0.84 (0.11) when the UK adult algorithm was applied and 0.70 (0.22), when the Australian adolescent algorithm was applied. The mean PedsQL score was 82.32 (13.14). The CHU9D-DK showed good internal consistency reliability (Cronbach's alpha = 0.803). Higher levels of health status and life satisfaction were significantly associated with higher CHU9D-DK utility scores regardless of which scoring algorithm was applied (p-values < 0.001). Students living with a disability/chronic disease exhibited significantly lower utility scores relative to their healthy peers (p-values < 0.05). Higher socio-economic status (approximated by financial situation and frequency of family vacations) was also associated with higher utility scores (p-values < 0.005). CONCLUSION The CHU9D-DK demonstrated good psychometric performance overall and shows potential as a valid and reliable instrument for assessing the HRQL of Danish young people. TRIAL REGISTRATION ClinicalTrials.gov identifier: NCT03391999, Registered 15 October 2017.

中文翻译：

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Child Health Utility 9D-DK 工具的结构效度。


背景技术相对于成人的应用，目前关于基于偏好的健康相关生活质量（HRQL）工具在年轻人群体中的应用的信息很少。儿童健康实用程序 9D (CHU9D) 是一款针对儿科的基于偏好的通用 HRQL 工具，最近已翻译为丹麦语 (CHU9D-DK)，并经过语言验证。本研究的目的是调查 CHU9D-DK 在丹麦高中生样本中的结构效度。方法 2018 年 1 月，丹麦高中的所有学生均被邀请参加一项网络调查（N = 272）。该调查包括 CHU9D-DK、儿科生活质量量表™ 4.0 通用核心量表 (PedsQL) 的年轻成人版本、自我报告的健康状况、是否存在残疾/慢性病、生活满意度和社会经济状况问题。 CHU9D-DK 实用分数是通过采用分别由英国成年人和澳大利亚青少年开发的两种评分算法生成的。对CHU9D-DK仪器的内部一致性、可靠性和结构效度进行了研究。结果 228 名 (84%) 学生同意参与并完成了调查。当应用英国成人算法时，CHU9D-DK 实用程序的平均值±（标准差）值为 0.84 (0.11)；当应用澳大利亚青少年算法时，CHU9D-DK 实用程序的平均值±（标准差）值为 0.70 (0.22)。 PedsQL 平均得分为 82.32 (13.14)。 CHU9D-DK 显示出良好的内部一致性信度（Cronbach's alpha = 0.803）。无论应用哪种评分算法，较高水平的健康状况和生活满意度与较高的 CHU9D-DK 效用分数显着相关（p 值 < 0.001）。 与健康同龄人相比，患有残疾/慢性病的学生的效用得分显着较低（p 值 < 0.05）。较高的社会经济地位（根据财务状况和家庭度假频率估算）也与较高的效用得分相关（p 值 < 0.005）。结论 CHU9D-DK 总体上表现出良好的心理测量性能，并显示出作为评估丹麦年轻人 HRQL 的有效且可靠的工具的潜力。试验注册 ClinicalTrials.gov 标识符：NCT03391999，注册于 2017 年 10 月 15 日。