In recent years, visible light driven enantioselective chemical transformations have emerged as new additions to the toolkit of synthetic chemists to accomplish more efficient assembly of chiral molecules. Nonetheless, implementing precise stereocontrol on photoinduced intermolecular radical coupling process remains arduous. Recent studies unveil the underexplored competence of chiral phosphoric acid for this class of asymmetric photoredox reactions, endowed by its capability as a bifunctional H‐bonding catalyst for synchronous interaction with radical intermediate and substrate while channeling the cross‐coupling in a highly enantioselective manner. This paper highlights the recent advances, future outlook as well as the prospective challenges in this research area.

中文翻译：

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手性磷酸为对映选择性光氧化还原催化创造了广阔的机遇

近年来，可见光驱动的对映选择性化学转化作为合成化学家工具包的新添加物出现，以实现更有效的手性分子组装。然而，在光诱导的分子间自由基偶联过程中实现精确的立体控制仍然是艰巨的。最近的研究揭示了手性磷酸在这类不对称光氧化还原反应中的未开发能力，这归功于其作为双官能氢键催化剂与自由基中间体和底物同步相互作用的能力，同时以高度对映选择性的方式引导交叉偶联。本文重点介绍了该研究领域的最新进展，未来展望以及未来的挑战。