An Overview on the Toxicological Properties of Ionic Liquids toward Microorganisms.,Biotechnology Journal

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An Overview on the Toxicological Properties of Ionic Liquids toward Microorganisms.
Biotechnology Journal ( IF 3.2 ) Pub Date : 2020-01-13 , DOI: 10.1002/biot.201900073
Magaret Sivapragasam ₁ , Muhammad Moniruzzaman _{2,

3} , Masahiro Goto _{4,

5}

Affiliation

Ionic liquids (ILs), a class of materials with unique physicochemical properties, have been used extensively in the fields of chemical engineering, biotechnology, material sciences, pharmaceutics, and many others. Because ILs are very polar by nature, they can migrate into the environment with the possibility of inclusion in the food chain and bioaccumulation in living organisms. However, the chemical natures of ILs are not quintessentially biocompatible. Therefore, the practical uses of ILs must be preceded by suitable toxicological assessments. Among different methods, the use of microorganisms to evaluate IL toxicity provides many advantages including short generation time, rapid growth, and environmental and industrial relevance. This article reviews the recent research progress on the toxicological properties of ILs toward microorganisms and highlights the computational prediction of various toxicity models.

中文翻译：

离子液体对微生物的毒理学特性概述。

离子液体（ILs）是一类具有独特物理化学性质的材料，已广泛用于化学工程，生物技术，材料科学，制药和许多其他领域。由于IL本质上具有极强的极性，因此它们可以迁移到环境中，并可能包含在食物链中以及在生物体内生物富集。但是，白介素的化学性质并不是典型的生物相容性。因此，ILs的实际使用必须先进行适当的毒理学评估。在不同的方法中，使用微生物评估IL毒性具有许多优势，包括生成时间短，生长迅速以及与环境和工业相关。

更新日期：2020-01-13

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