Antiretroviral therapy (ART) adherence and retention in care are crucial and poorly understood challenges to the care of women living with HIV in the USA, particularly in women with perinatally acquired HIV. Children with perinatally acquired HIV now survive to adulthood and have pregnancies of their own, but not without both medical and behavioural health consequences. ^{,  ,}  In addition to the medical co-morbidities of chronic HIV infection, adolescents and young adults who have grown up with perinatally acquired HIV often have virological resistance from inconsistent long-term ART use. These young people face a lifetime of chronic disease, as well as the associated stigma and resulting behavioural consequences and health comorbidities. This patient population also tends toward more high-risk sexual behaviour, mental illness, and substance abuse than both HIV-exposed but uninfected peers, and peers with behaviourally-acquired HIV. ^,  Pregnancy and pregnancy-associated adverse outcomes remain understudied in these patients, as does post-partum adherence and retention in medical care.

中文翻译：

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感染艾滋病毒的产后妇女的依从性。


抗逆转录病毒治疗 (ART) 的坚持和护理保留对于美国艾滋病毒感染妇女的护理至关重要，但人们对此知之甚少，尤其是围产期感染艾滋病毒的妇女。围产期感染艾滋病毒的儿童现在可以存活到成年并自己怀孕，但并非没有医疗和行为健康后果。 ^{, ,}除了慢性艾滋病毒感染的医学并发症外，在围产期感染艾滋病毒的青少年和年轻人通常会因长期不一致的抗逆转录病毒治疗而产生病毒学耐药性。这些年轻人面临着终生的慢性疾病，以及相关的耻辱和由此产生的行为后果和健康合并症。与暴露于艾滋病毒但未感染的同龄人以及通过行为获得艾滋病毒的同龄人相比，这些患者群体还倾向于出现更高风险的性行为、精神疾病和药物滥用。这些患者的妊娠和妊娠相关不良后果^以及产后依从性和保留医疗护理的情况仍未得到充分研究。