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Absence of Coronary Artery Calcification in Middle Aged Familial Hypercholesterolemia Patients Without Atherosclerotic Cardiovascular Disease.
JACC: Cardiovascular Imaging ( IF 12.8 ) Pub Date : 2020-04-01 , DOI: 10.1016/j.jcmg.2019.11.001 Reed Mszar , Gowtham R. Grandhi , Javier Valero-Elizondo , Salim S. Virani , Ron Blankstein , Michael Blaha , Pedro Mata , Marcio H. Miname , Khalid Al Rasadi , Harlan M. Krumholz , Raul D. Santos , Khurram Nasir
JACC: Cardiovascular Imaging ( IF 12.8 ) Pub Date : 2020-04-01 , DOI: 10.1016/j.jcmg.2019.11.001 Reed Mszar , Gowtham R. Grandhi , Javier Valero-Elizondo , Salim S. Virani , Ron Blankstein , Michael Blaha , Pedro Mata , Marcio H. Miname , Khalid Al Rasadi , Harlan M. Krumholz , Raul D. Santos , Khurram Nasir
Heterozygous familial hypercholesterolemia (HeFH), an autosomal dominant genetic disorder affecting nearly 1 in 250 individuals, is a major cause of premature atherosclerotic cardiovascular disease (ASCVD) ([1][1]). In the absence of treatment, patients with HeFH manifest a nearly 20-fold higher
中文翻译:
无动脉粥样硬化性心脏病的中年家族性高胆固醇血症患者冠状动脉钙化的缺乏。
杂合子家族性高胆固醇血症(HeFH)是一种常染色体显性遗传疾病,可影响250个人中的近1个人,是导致过早动脉粥样硬化性心血管疾病(ASCVD)的主要原因([1] [1])。在不进行治疗的情况下,HeFH患者的病情高出近20倍
更新日期:2020-04-01
中文翻译:
无动脉粥样硬化性心脏病的中年家族性高胆固醇血症患者冠状动脉钙化的缺乏。
杂合子家族性高胆固醇血症(HeFH)是一种常染色体显性遗传疾病,可影响250个人中的近1个人,是导致过早动脉粥样硬化性心血管疾病(ASCVD)的主要原因([1] [1])。在不进行治疗的情况下,HeFH患者的病情高出近20倍