Conventional single thermal nature of phase change materials (PCMs) seriously obstructs their frontier applications. Herein, we designed advanced carbon nanotube (CNT) bundles assembled flexible hierarchical framework based phase change material composites for high-performance thermotherapy of allergic rhinitis. Hierarchically interconnected 3D freestanding flexible CNT sponge was constructed via a facile organic solvent-free route using table salt as a sacrificial template. The resulting hierarchical CNT sponge serves as an ideal compatible supporting host and polyethylene glycol (PEG) serves as an excellent thermal energy guest. Subsequently, we designed advanced portable integrated functional mask consisting of outer air purification layer and inner thermal regulation layer for the thermotherapy of allergic rhinitis, in which pristine CNT sponge serves as an excellent particulate matter capturer and PEG-infiltrated CNT sponge serves as a superior thermal regulator. Strikingly, our uniquely constructed flexible CNT sponge-involved composite PCMs assisted by polyvinylidene fluoride (PVDF) harvest high-performance thermotherapy (∼33 min of the plateau at ∼43.5 °C). The corresponding medical results (HE staining and Wrights staining) further indicate that our designed thermotherapy mask can significantly reduce the inflammatory injury of nasal mucosa. Additionally, pristine hierarchical CNT sponge guarantees the inhaled air quality and enhances the thermotherapy effect. This synthetic strategy can be scaled up for large-scale production. This novel functional host-guest strategy creates an innovative platform for developing advanced multifunctional PCMs with multiple fascinating peculiarities and desired functional properties and teaches an old dog new tricks.

相变材料（PCM）的常规单一热性质严重阻碍了它们的前沿应用。在这里，我们设计了先进的碳纳米管（CNT）束，组装了基于柔性分层框架的相变材料复合材料，用于过敏性鼻炎的高性能热疗。使用食用盐作为牺牲模板，通过不带有机溶剂的简便方法构建了分层互连的3D独立式柔性CNT海绵。所得的分层CNT海绵可作为理想的相容性支撑基质，而聚乙二醇（PEG）则可作为出色的热能客体。随后，我们设计了由外部空气净化层和内部热调节层组成的高级便携式集成功能面罩，用于过敏性鼻炎的热疗，其中，原始的CNT海绵可作为出色的颗粒物捕获器，而PEG渗透的CNT海绵则可作为出色的热调节剂。令人惊讶的是，在聚偏二氟乙烯（PVDF）的辅助下，我们独特构造的柔性CNT海绵参与的复合PCM收获了高效热疗法（在约43.5°C的高原时间约33分钟）。相应的医学结果（HE染色和Wrights染色）进一步表明，我们设计的热疗面罩可以显着减少鼻粘膜的炎症损伤。此外，原始的分层CNT海绵可确保吸入的空气质量并增强热疗效果。这种综合策略可以扩大规模以进行大规模生产。