The endothelial glycocalyx (EG) is the thin sugar-based lining on the apical surface of endothelial cells. It has been linked to the physiological functioning of the microcirculation and has been found to be damaged in critical illness and after acute care surgery. This review aims to describe the role of EG in severely injured patients undergoing surgery, discuss specific situations (e.G. major trauma, hemorrhagic shock, trauma induced coagulopathy) as well as specific interventions commonly applied in these patients (e.g. fluid therapy, transfusion) and specific drugs related to perioperative medicine with regard to their impact on EG.EG in acute care surgery is exposed to damage due to tissue trauma, inflammation, oxidative stress and inadequate fluid therapy. Even though some interventions (transfusion of plasma, human serum albumin, hydrocortisone, sevoflurane) are described as potentially EG protective there is still no specific treatment for EG protection and recovery in clinical medicine.The most important principle to be adopted in routine clinical practice at present is to acknowledge the fragile structure of the EG and avoid further damage which is potentially related to worsened clinical outcome.

中文翻译：

---

急性护理手术中的内皮糖萼-麻醉医师在临床实践中需要了解的内容。

内皮糖萼（EG）是内皮细胞顶表面上的薄糖基衬里。它与微循环的生理功能有关，已发现在严重疾病和急性护理手术后会受损。这篇综述旨在描述EG在重伤患者中的作用，讨论具体情况（例如，重大外伤，出血性休克，外伤引起的凝血病）以及在这些患者中通常采用的特殊干预措施（例如液体疗法，输血）和特异性与围手术期医学有关的药物对EG的影响。在急性护理手术中EG由于组织创伤，炎症，氧化应激和液体治疗不足而受到损害。即使采取了一些干预措施（输血，人血清白蛋白，