Background Safety, environmental and economic setbacks are driving industries to find greener approaches to extract bioactive compounds from natural resources. Pressurized hot water extraction (PHWE) is among the solvent free and efficient methods for extracting bioactive compounds. Experimental In this study, the suitability of PHWE for extracting bioactive compounds such as phenolics, hydrolysable tannins and flavonoids from Phyllanthus tenellus was investigated by UPLC-qTOF-MS. Results Solvent properties of water are significantly increased through imposing temperature at 121 °C and pressure at 15 p.s.i. Pressurized hot water extraction obtained 991-folds higher hydrolysable tannins than methanol extraction. Conclusion The extraction yields of hydrolysable tannins with PHWE was almost double of absolute methanol extraction.

中文翻译：

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加压热水提取 Phyllanthus tenellus Roxb 中的可水解单宁。

背景 安全、环境和经济方面的挫折正在推动行业寻找更环保的方法从自然资源中提取生物活性化合物。加压热水萃取 (PHWE) 是提取生物活性化合物的无溶剂且有效的方法之一。实验 在本研究中，采用 UPLC-qTOF-MS 研究了 PHWE 对从柔毛下叶中提取酚类、可水解单宁和类黄酮等生物活性化合物的适用性。结果 通过在 121 °C 的温度和 15 psi 的压力下施加压力，水的溶剂性质显着提高 加压热水萃取获得的可水解单宁比甲醇萃取高 991 倍。结论 PHWE对水解单宁的提取率几乎是无水甲醇提取的两倍。