The highly atom efficient three-component reaction of aldehydes, secondary amines and acetylenes to form propargylamines (A³-coupling) has been studied with twelve readily available copper-containing minerals. It was found that the reaction could easily be performed in the presence of malachite, brochantite, chrysocolla and azurite in toluene at reflux. The desired products were obtained in good to excellent yields.

中文翻译：

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易获得的含铜矿物质催化A ³偶联反应的研究。炔丙基胺的合成

用十二种容易获得的含铜矿物研究了醛，仲胺和乙炔形成炔丙基胺的高度原子高效的三组分反应（A ³偶联）。发现该反应可以容易地在孔雀石，Brantantite，Chrysocolla和Azurite在甲苯中在回流下存在下进行。以良好至优异的产率获得了所需的产物。