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DNA Modification Readers and Writers and Their Interplay.
Journal of Molecular Biology ( IF 4.7 ) Pub Date : 2019-12-20 , DOI: 10.1016/j.jmb.2019.12.018
Cathia Rausch 1 , Florian D Hastert 1 , M Cristina Cardoso 1
Affiliation  

Genomic DNA is modified in a postreplicative manner and several modifications, the enzymes responsible for their deposition as well as proteins that read these modifications, have been described. Here, we focus on the impact of DNA modifications on the DNA helix and review the writers and readers of cytosine modifications and how they interplay to shape genome composition, stability, and function.

中文翻译:

DNA 修饰读者和作家及其相互作用。

基因组 DNA 以复制后方式进行修饰,并且已经描述了几种修饰,负责它们沉积的酶以及读取这些修饰的蛋白质。在这里,我们重点关注 DNA 修饰对 DNA 螺旋的影响,并回顾胞嘧啶修饰的作者和读者,以及它们如何相互作用以塑造基因组组成、稳定性和功能。
更新日期:2019-12-20
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