BACKGROUND To investigate the magnetic resonance imaging (MRI) features of orbital Langerhans cell histiocytosis (LCH) to improve diagnostic accuracy. METHODS We retrospectively reviewed clinical manifestations and MRI findings of 23 patients with histopathology-confirmed LCH of the orbit. The findings were evaluated for the following: (a) symptoms, (b) disease duration, (c) location, (d) configuration, (e) margin, (f) MR imaging signal intensity and enhanced performance. RESULTS Eighteen patients (78%) in our series were male, only five (22%) patients were female, and the mean age at presentation was 6.3 years. The common symptoms include swollen eyelids, exophthalmos, and a palpable mass. Fourteen patients presented with swollen eyelids and/or exophthalmos. Twenty-two cases involved unilateral orbits, and one case involved bilateral orbits. In our study, there was one patient with cough and expectoration, and one patient with polydipsia and polyuria. Lesions were located in the superior or superlateral orbital roof of seventeen patients (74%). Lesions formed masses or irregular shapes. The 12 out of 23 (52.2%) cases appeared heterogeneous isointense and 10 out of 23 (43.5%) cases showed iso-hypointense on T1-weighted imaging, there were 15 out of 23 (65.2%) cases showed hyper-hypointense mixed signals on T2-weighted imaging. 7 cases found patchy hyperintense signal on T1WI, and 11 cases showed markedly hyperintense signal near the edge of lesions on T2WI. After enhancement, 21 out of 23 (91.3%) cases lesions presented marked enhancement at the edges and the surrounding tissues, and with heterogeneous obvious enhancement of the lesion center. Besides, four cases lesions were surrounded by a low circular signal. CONCLUSION There were several characteristics MRI features that can provide crucial information for clinicians and improve our understanding and the diagnostic accuracy of the orbital LCH.

中文翻译：

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眼眶朗格汉斯细胞组织细胞增生症的MR成像特征。

背景技术要研究眼眶朗格汉斯细胞组织细胞增生症（LCH）的磁共振成像（MRI）特征，以提高诊断准确性。方法我们回顾性回顾了23例经组织病理学证实为眼眶LCH的患者的临床表现和MRI表现。对结果进行了以下评估：（a）症状，（b）疾病持续时间，（c）位置，（d）配置，（e）边缘，（f）MR成像信号强度和增强的性能。结果我们系列中的18例患者（78％）为男性，只有5例（22％）患者为女性，就诊时的平均年龄为6.3岁。常见症状包括眼睑肿胀，眼球突出和明显肿块。14名患者出现眼睑和/或眼球突出。22例涉及单侧轨道，1例涉及双侧轨道。在我们的研究中，有1名患者出现咳嗽和咳痰，还有1名患者有饮酒和多尿。病变位于十七名患者（74％）的眶上或眶上。病变形成肿块或不规则形状。23例中有12例（52.2％）表现出异构等强度，23例中有10例（43.5％）在T1加权成像上表现出等低点，23例中有15例（65.2％）表现出超低等混合信号在T2加权成像上。7例在T1WI上发现斑片性高信号，11例在T2WI病灶边缘附近显示出明显的高信号。增强后，在23例病例中，有21例（91.3％）的病变在边缘和周围组织中表现出明显的增强，并且病变中心的异质性明显增强。除了，4例病灶周围有低圆形信号。结论MRI具有多种特征，可以为临床医生提供重要信息，并增进我们对眼眶LCH的了解和诊断准确性。