BACKGROUND Hospital-acquired infection (HAI) is a serious complication of neurosurgery. In recent years, the medical body has paid increasing attention to this issue. AIM We investigated the status of HAIs in patients who had undergone surgery for intracranial aneurysms and analysed their risk factors. METHODS A retrospective analysis was carried out on the medical records of 542 patients with intracranial aneurysms after they were admitted for neurosurgery at Xuanwu Hospital of Capital Medical University between January and December 2016. Cases studied were divided into an infection group and a control group. Logistic regression analysis of the data was carried out. FINDINGS Of the 542 patients with intracranial aneurysms who underwent surgery, 77 HAIs occurred in 64 patients, with an infection prevalence of 11.8% and prevalence of infection cases of 14.2%. Logistic regression showed that an admission Glasgow Coma Scale (GCS) score of less than 8 points (odds ratio = 4.261, 95% confidence interval 1.102-16.476), hyperglycaemia (2.759, 1.159-6.564), hypothermia treatment (6.557, 2.244-19.159), and central venous catheterisation (CVC) (8.853, 2.860-27.398) were independent risk factors for HAIs in patients with intracranial aneurysm who underwent surgery. CONCLUSION Being comatose upon hospital admission, having hyperglycaemia or hypothermia, and indwelling CVC are major risk factors for HAIs in patients undergoing surgery for intracranial aneurysms.

中文翻译：

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影响颅内动脉瘤术后患者医院获得性感染的因素分析。

背景技术医院获得性感染（HAI）是神经外科手术的严重并发症。近年来，医疗机构对此问题越来越关注。目的我们调查了颅内动脉瘤手术患者中HAIs的状况，并分析了其危险因素。方法回顾性分析2016年1月至2016年12月在首都医科大学宣武医院接受神经外科手术治疗的542例颅内动脉瘤患者的病历。研究将病例分为感染组和对照组。进行数据的逻辑回归分析。结果在542例接受颅内动脉瘤手术的患者中，有64例患者发生77例HAI，感染率为11。8％，感染率14.2％。Logistic回归分析显示格拉斯哥昏迷量表（GCS）得分低于8分（优势比= 4.261，95％置信区间1.102-16.476），高血糖症（2.759，1.159-6.564），体温过低治疗（6.557，2.244-19.159） ）和中央静脉导管（CVC）（8.853，2.860-27.398）是接受颅内动脉瘤手术的患者HAIs的独立危险因素。结论入院时昏迷，血糖过高或体温过低，CVC留置是颅内动脉瘤手术患者HAIs的主要危险因素。低温治疗（6.557，2.244-19.159）和中心静脉导管（CVC）（8.853，2.860-27.398）是接受颅内动脉瘤手术的患者HAIs的独立危险因素。结论入院时昏迷，血糖过高或体温过低，CVC留置是颅内动脉瘤手术患者HAIs的主要危险因素。低温治疗（6.557，2.244-19.159）和中心静脉导管（CVC）（8.853，2.860-27.398）是接受颅内动脉瘤手术的HAI患者的独立危险因素。结论入院时昏迷，血糖过高或体温过低，CVC留置是颅内动脉瘤手术患者HAIs的主要危险因素。