While hydrogen polysulfides (H2Sn, n ≥ 2) are believed to play regulatory roles in biology, their fundamental chemistry and reactivity are still poorly understood. Compounds that can produce H2Sn are useful tools. In this work we found that H2S2 could be effectively produced from diacyl disulfide precursors, triggered by certain nucleophiles, in both aqueous solutions and organic solvents. This method was used to explore redox reactions of H2S2, such as scavenging 1,1-diphenyl-2-picrylhydrazyl radical (DPPH) and reduction of tetrazines.

中文翻译：

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二酰基二硫化物作为过硫化氢 (H2S2) 的前体。

虽然多硫化氢（H2Sn，n ≥ 2）被认为在生物学中发挥调节作用，但对其基本化学和反应性仍知之甚少。能够产生 H2Sn 的化合物是有用的工具。在这项工作中，我们发现在水溶液和有机溶剂中，在某些亲核试剂的触发下，二酰基二硫醚前体可以有效地产生 H2S2。该方法用于探索 H2S2 的氧化还原反应，例如清除 1,1-二苯基-2-三硝基苯肼自由基 (DPPH) 和还原四嗪。