COPII vesicles mediate anterograde ER-Golgi traffic of newly synthesized proteins in nutrient rich conditions. An accumulating body of results indicates that the secretory COPII vesicles can be shifted to the roles in autophagosome formation and selective ER-phagy (autophagy of ER), depending on their specific subunits, in response to environmental stresses. In this mini-review, we summarize and discuss the multifaceted roles of COPII vesicles in autophagy and the underlying molecular mechanisms.

中文翻译：

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COPII亚基在自噬中的多重作用。

COPII囊泡在营养丰富的条件下介导新合成蛋白质的顺行性ER-高尔基体运输。大量的结果表明，分泌的COPII囊泡可根据环境中的特定亚基，转变为自噬体形成和选择性ER吞噬（ER的自噬）的作用。在此迷你审查中，我们总结和讨论了COPII囊泡在自噬中的多方面作用以及潜在的分子机制。