In many organisms, primordial germ cells (PGCs) are specified at a different location than where the gonad forms, meaning that PGCs must migrate toward the gonad within the early developing embryo. Following species-specific paths, PGCs can be passively carried by surrounding tissues and also perform active migration. When PGCs actively migrate through and along a variety of embryonic structures in different organisms, they adopt an ancestral robust migration mode termed "amoeboid motility", which allows cells to migrate within diverse environments. In this review, we discuss the possible significance of the PGC migration process in facilitating the evolution of animal body shape. In addition, we summarize the latest findings relevant for the molecular and cellular mechanisms controlling the movement and the directed migration of PGCs in different species.

中文翻译：

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生殖细胞迁移-进化问题和当前的了解。

在许多生物中，原始生殖细胞（PGC）的位置与性腺形成的位置不同，这意味着PGC必须在早期发育的胚胎内向性腺迁移。遵循物种特定的路径，PGC可以被周围组织被动携带，也可以主动迁移。当PGC在不同生物体中通过各种胚胎结构主动迁移时，它们会采用祖先的稳健迁移模式，称为“类阿米巴运动”，该模式可让细胞在不同的环境中迁移。在这篇综述中，我们讨论了PGC迁移过程在促进动物体形演变中的可能意义。此外，