The effect of oral administration of all-E-isomer-rich and Z-isomer-rich lycopene on liver accumulation in mice was investigated. When a diet rich in the Z-isomers was administered for 4 weeks, the total lycopene concentration in the liver was more than 3 times higher than that of all-E-isomer administration. This result clearly indicates that lycopene Z-isomers show greater bioavailability and/or liver accumulation than the all-E-isomer in mice.

中文翻译：

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番茄红素的Z-异构体在小鼠中比全E-异构体表现出更大的肝脏积累。

研究了口服全富E-异构体和富Z-异构体的番茄红素对小鼠肝脏蓄积的影响。当饮食富含Z-异构体4周时，肝脏中番茄红素的总浓度比全E异构体高3倍以上。该结果清楚地表明，番茄红素Z-异构体在小鼠中显示出比全E-异构体更高的生物利用度和/或肝脏蓄积。