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HIV‐associated morbidity and mortality in a setting of high ART coverage: prospective surveillance results from a district hospital in Botswana
Journal of the International AIDS Society ( IF 6 ) Pub Date : 2019-12-01 , DOI: 10.1002/jia2.25428
Tomer Barak 1, 2, 3 , Dayna T Neo 4 , Neo Tapela 1, 5, 6 , Patricia Mophuthegi 1 , Rebbeca Zash 1, 7 , Ketenga Kalenga 3 , Melissa Eo Perry 8 , Mompati Malane 1 , Joseph Makhema 1 , Shahin Lockman 1, 9 , Roger Shapiro 1, 7, 9
Affiliation  

Antiretroviral therapy (ART) has significantly improved survival in Africa in recent years. In Botswana, where adult HIV prevalence is 21.9%, AIDS‐related mortality is estimated to have declined by 58% between 2005 and 2013 following the initial wide‐spread introduction of ART, and ART coverage has steadily increased reaching 84% in 2016. However, there remains little data about the burden of HIV and its impact on mortality in the hospital setting where most deaths occur. We aimed to describe the burden of HIV and related morbidity and mortality among hospitalized medical patients in a district hospital in southern Botswana in the era of widespread ART coverage.

中文翻译:

ART 高覆盖率环境下的 HIV 相关发病率和死亡率:来自博茨瓦纳地区医院的前瞻性监测结果

近年来,抗逆转录病毒疗法 (ART) 显着提高了非洲的生存率。在博茨瓦纳,成人艾滋病毒流行率为 21.9%,在最初广泛引入抗病毒治疗后,2005 年至 2013 年间,与艾滋病相关的死亡率估计下降了 58%,抗病毒治疗的覆盖率稳步上升,2016 年达到 84%。然而,在大多数死亡发生的医院环境中,关于 HIV 负担及其对死亡率影响的数据仍然很少。我们旨在描述在广泛接受抗病毒治疗的时代博茨瓦纳南部地区医院住院患者的 HIV 负担以及相关的发病率和死亡率。
更新日期:2019-12-01
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