We conducted a systematic review and meta-analysis of randomized controlled trials examining the effect of vitamin C and/or E on exercise-induced training adaptations. Medline, Embase and SPORTDiscus databases were searched for articles from inception until June 2019. Inclusion criteria was studies in adult humans where vitamin C and/or E had to be consumed alongside a supervised exercise training program of ≥4 weeks. Nine trials were included in the analysis of aerobic exercise adaptations and nine for resistance training (RT) adaptations. Vitamin C and/or E did not attenuate aerobic exercise induced improvements in maximal aerobic capacity ($\dot{V}$O_2max) (SMD −0.14, 95% CI: −0.43 to 0.15, P = 0.35) or endurance performance (SMD −0.01, 95% CI: −0.38 to 0.36, P = 0.97). There were also no effects of these supplements on lean mass and muscle strength following RT (SMD −0.07, 95% CI: −0.36 to 0.23, P = 0.67) and (SMD −0.15, 95% CI: −0.16 to 0.46, P = 0.35), respectively. There was also no influence of age on any of these outcomes (P > 0.05). These findings suggest that vitamin C and/or E does not inhibit exercise-induced changes in physiological function. Studies with larger sample sizes and adequate power are still required.

我们对随机对照试验进行了系统的回顾和荟萃分析，研究了维生素C和/或E对运动诱发的训练适应性的影响。从开始到2019年6月，从Medline，Embase和SPORTDiscus数据库中搜索文章。纳入标准是对成年人进行的研究，其中必须摄入维生素C和/或E，并进行≥4周的有监督运动训练。有氧运动适应性分析中包括九项试验，而阻力训练（RT）适应性中包括九项试验。维生素C和/或E不会减弱有氧运动引起的最大有氧运动能力的改善（$\dot{\mathrm{伏特}}$O _2max）（SMD -0.14，95％CI：-0.43至0.15，P  = 0.35）或耐力性能（SMD -0.01，95％CI：-0.38至0.36，P  = 0.97）。这些补充剂对RT后的瘦体重和肌肉力量也没有影响（SMD -0.07，95％CI：-0.36至0.23，P  = 0.67）和（SMD -0.15，95％CI：-0.16至0.46，P  = 0.35）。年龄对这些结局也没有影响（P  > 0.05）。这些发现表明，维生素C和/或E不会抑制运动引起的生理功能变化。仍然需要使用更大的样本量和足够的功效进行研究。