Intestinal homeostasis relies on the reciprocal crosstalk between enteric neurons and immune cells, which together form neuro-immune units that occupy distinct anatomical niches within the gut. Here we will review the recent advances in our understanding of neuro-immune crosstalk within the gut, with focus on macrophages, mast cells and innate lymphoid cells. In particular, we will discuss the role of neuron-immune cell crosstalk in homeostasis, and how aberrant communication may underlie disease in the gastro-intestinal tract.

中文翻译：

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肠神经免疫相互作用：集中于巨噬细胞，肥大细胞和先天淋巴样细胞。

肠内动态平衡依赖于肠神经元与免疫细胞之间的相互串扰，它们共同形成神经免疫单位，占据肠道内独特的解剖壁ni。在这里，我们将回顾我们对肠道内神经免疫串扰的理解的最新进展，重点是巨噬细胞，肥大细胞和先天性淋巴样细胞。特别是，我们将讨论神经元免疫细胞串扰在体内平衡中的作用，以及异常的交流可能是胃肠道疾病的基础。