Schistosomiasis, a neglected tropical disease, is a major cause of chronic morbidity and disability, and premature death. The hepatosplenic form of schistosomiasis is characterized by hepatosplenomegaly, liver fibrosis, portal hypertension, and esophageal varices, whose rupture may cause bleeding and death. We review currently available abdominal imaging modalities and describe their basic principles, strengths, weaknesses, and usefulness in the assessment of hepatosplenic schistosomiasis (HSS). Advanced imaging methods are presented that could be of interest for hepatosplenic schistosomiasis evaluation by yielding morphological, functional, and molecular parameters of disease progression. We also provide a comprehensive view of preclinical imaging studies and current research objectives such as parasite visualization in hosts, follow-up of the host's immune response, and development of noninvasive quantitative methods for liver fibrosis assessment.

中文翻译：

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肝脾血吸虫病的临床和临床前成像。

血吸虫病是一种被忽视的热带病，是导致慢性发病和残疾以及过早死亡的主要原因。血吸虫病的肝脾形式的特征是肝脾肿大，肝纤维化，门脉高压和食管静脉曲张，破裂可能导致出血和死亡。我们回顾了当前可用的腹部成像方式，并描述了它们的基本原理，优点，缺点和在评估肝脾血吸虫病（HSS）中的有用性。提出了先进的成像方法，通过产生疾病进展的形态，功能和分子参数，可能对肝脾血吸虫病的评估感兴趣。我们还提供了临床前影像学研究和当前研究目标（例如宿主中的寄生虫可视化）的全面视图，