BACKGROUND Endoscopic ultrasound is useful for obtaining high-resolution images of pancreaticobiliary diseases, but is not readily available for physical checkups. In this study, we evaluated the safety and efficacy of single-session esophagogastroduodenoscopy and endoscopic ultrasound in the detection of upper-gastrointestinal and pancreaticobiliary diseases using a forward-viewing radial scan ultrasonic endoscope. METHODS A total of 148 patients who were scheduled for upper-gastrointestinal screening using an endoscope were prospectively included. All patients were examined by EUS in combination with EGD using a forward-viewing radial scan ultrasonic endoscope. The primary endpoint was the safety of the procedures. The secondary endpoints were the prevalence of diseases, the basal imaging capability of EUS, the procedure time, total dose of propofol, and the correlation between background factors and the prevalence of pancreatic disease. The imaging capability at each region was scored as 0 (invisible) to 2 (sufficient visualization to evaluate the organs). RESULTS Intraoperative hypotension occurred as an adverse event of intravenous anesthesia in one patient. There were 82 pancreaticobiliary findings and 165 upper-gastrointestinal findings (malignancy not included). Follicular lymphoma of the intra-abdominal lymph nodes was detected in one patient. The mean imaging scores of each section were 1.95 (pancreatic head and papilla), 2.0 (pancreatic body), 1.99 (pancreatic tail), and 1.89 (common bile duct and gallbladder). Age, history of diabetes mellitus, and smoking history were significantly associated with the prevalence of pancreatic diseases. CONCLUSION The simultaneous performance of EGD and EUS using a new ultrasonic endoscope is tolerable and safe for upper-gastrointestinal and pancreaticobiliary screening.

中文翻译：

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单次食管胃十二指肠镜和内镜超声使用前视放射扫描超声内窥镜。

背景技术内窥镜超声可用于获得胰胆管疾病的高分辨率图像，但不适用于身体检查。在这项研究中，我们使用前瞻性径向扫描超声内窥镜评估了单次食管胃十二指肠镜和内镜超声在检测上消化道和胰胆管疾病中的安全性和有效性。方法前瞻性纳入了预定使用内窥镜进行上消化道筛查的148例患者。所有患者均接受EUS联合EGD检查，并使用前视径向扫描超声内窥镜进行检查。主要终点是手术的安全性。次要终点是疾病的患病率，EUS的基础成像能力，手术时间，异丙酚的总剂量，以及背景因素与胰腺疾病患病率之间的相关性。每个区域的成像能力评分为0（不可见）至2（可视化程度足以评估器官）。结果一名患者发生术中低血压是由于静脉麻醉的不良事件。共有82例胰胆管检查结果和165例上消化道检查结果（不包括恶性肿瘤）。一名患者检测到腹腔内淋巴结滤泡性淋巴瘤。每个部分的平均成像评分分别为1.95（胰头和乳头），2.0（胰体），1.99（胰尾）和1.89（胆总管和胆囊）。年龄，糖尿病史和吸烟史与胰腺疾病的患病率显着相关。