BACKGROUND Intravenous anesthesia has been reported to have a favorable effect on the prognosis of cancer patients. This study was performed to analyze data regarding the relation between anesthetics and the prognosis of cancer patients in our hospital. METHODS The medical records of patients who underwent surgical resection for gastric, lung, liver, colon, and breast cancer between January 2006 and December 2009 were reviewed. Depending on the type of anesthetic, it was divided into total intravenous anesthesia (TIVA) or volatile inhaled anesthesia (VIA) group. The 5-year overall survival outcomes were analyzed by log-rank test. Cox proportional hazards modeling was used for sensitivity. RESULTS The number of patients finally included in the comparison after propensity matching came to 729 in each group. The number of surviving patients at 5 years came to 660 (90.5%) in the TIVA and 673 (92.3%) in the VIA. The type of anesthetic did not affect the 5-year survival rate according to the log-rank test (P = 0.21). Variables associated with a significant increase in the hazard of death after multivariable analysis were male sex and metastasis at surgery. CONCLUSIONS There were no differences in 5-year overall survival between two groups in the cancer surgery. TRIAL REGISTRATION Trial registration: CRIS KCT0004101. Retrospectively registered 28 June 2019.

中文翻译：

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癌症手术后的麻醉剂和长期生存率-静脉内麻醉与挥发性麻醉相比：一项回顾性研究。

背景技术据报道，静脉麻醉对癌症患者的预后具有有利的作用。本研究旨在分析有关麻醉药与我院癌症患者预后之间关系的数据。方法回顾性分析了2006年1月至2009年12月间因胃癌，肺癌，肝癌，结肠癌和乳腺癌进行手术切除的患者的病历。根据麻醉剂的类型，分为全静脉麻醉（TIVA）或挥发性吸入麻醉（VIA）组。通过对数秩检验分析5年总生存结局。考克斯比例风险建模用于敏感性。结果倾向匹配后，最终纳入比较的患者人数为每组729名。在TIVA中5年存活的患者人数为660（90.5％），在VIA中为673（92.3％）。根据对数秩检验，麻醉剂的类型不影响5年生存率（P = 0.21）。多变量分析后与死亡危险显着增加相关的变量是男性和手术转移。结论两组在癌症手术中的5年总生存率没有差异。试用注册试用注册：CRIS KCT0004101。追溯注册于2019年6月28日。多变量分析后与死亡危险显着增加相关的变量是男性和手术转移。结论两组在癌症手术中的5年总生存率没有差异。试用注册试用注册：CRIS KCT0004101。追溯注册于2019年6月28日。多变量分析后与死亡危险显着增加相关的变量是男性和手术转移。结论两组在癌症手术中的5年总生存率没有差异。试用注册试用注册：CRIS KCT0004101。追溯注册于2019年6月28日。