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NETs spread ever wider in rheumatic diseases.
Nature Reviews Rheumatology ( IF 29.4 ) Pub Date : 2019-12-18 , DOI: 10.1038/s41584-019-0352-1
Gustaf Wigerblad 1 , Mariana J Kaplan 1
Affiliation  

Dysregulation in the formation and/or clearance of neutrophil extracellular traps (NETs) is important in immune dysregulation and organ damage in chronic inflammatory conditions. Studies in 2019 have shown how certain genetic susceptibilities to autoimmunity can promote NET-mediated inflammation, and expanded the role for NETs in vascular damage and premature atherosclerosis.

中文翻译:

NET在风湿性疾病中的传播越来越广泛。

中性粒细胞胞外陷阱(NETs)的形成和/或清除失调在慢性炎症条件下的免疫失调和器官损伤中很重要。2019年的研究表明,对自身免疫的某些遗传敏感性如何促进NET介导的炎症,并扩大NET在血管损伤和过早的动脉粥样硬化中的作用。
更新日期:2019-12-19
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