An adolescent boy presented to the dermatology clinic with a 3-year history of penile edema and scrotal swelling that had suddenly worsened. His history was notable for Crohn disease that was diagnosed 4 years previously and managed with adalimumab after treatment with prednisone, 6-mercaptopurine, and infliximab failed. There was no lymphadenopathy and no history of trauma, infections, or instrumentation. The patient denied any history of urinary tract infection symptoms. He mentioned a feeling of incomplete evacuation but did not have any other gastrointestinal symptoms at the time of presentation. A physical examination revealed scrotal and penile edema, perianal swelling, and perineal swelling (Figure). A biopsy specimen was obtained, and results were compatible with extraintestinal Crohn disease.

一个青春期男孩到皮肤科诊所就诊，有3年的阴茎水肿和阴囊肿胀病史，但突然恶化。他的病史因克罗恩病而著称，克罗恩病已于4年前诊断，并在接受泼尼松，6-巯基嘌呤和英夫利昔单抗治疗失败后接受阿达木单抗治疗。没有淋巴结肿大，也没有外伤，感染或器械的病史。该患者否认有任何尿路感染症状的病史。他提到了疏散不完全的感觉，但在就诊时没有任何其他胃肠道症状。体格检查发现阴囊和阴茎水肿，肛周肿胀和会阴肿胀（图）。获得了活检标本，其结果与肠外克罗恩病相容。