We were pleased to receive the correspondence of Guggino et al 1 commenting on our recent publication.2 Their studies confirm our findings of an expansion of cells with an expression profile consistent with tissue-resident memory cells (TRMs) in synovial fluid of spondyloarthritis (SpA). They have added the valuable insight that these cells are also expanded in gut tissues of patients with SpA. The CD8+ T cell in question reported …

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回应：Guggino 等人的“肠道来源的 CD8+ 组织驻留记忆 T 细胞在 SpA 患者的外周血和滑膜中扩增”

我们很高兴收到 Guggino 等人 1 对我们最近发表的文章发表评论的信函。2 他们的研究证实了我们的发现，即在脊柱关节炎 (SpA) 滑液中，细胞扩增的表达谱与组织驻留记忆细胞 (TRM) 一致）。他们补充了一个有价值的见解，即这些细胞也在 SpA 患者的肠道组织中扩增。有问题的 CD8+ T 细胞报告了……