We read with great interest the correspondence from Didierlaurent et al 1 regarding our recent report on the association between vaccination and risk of gout flares using a case-crossover design.2 In particular, we appreciate the clarification that the authors provided regarding the unsolicited adverse events reported during the 30 days after each vaccination, including episodes of gout, with incident gout cases surpassing reports of recurrent gout flares. While this is a notable difference from our online case-crossover study which included only patients with known gout and assessed for recurrent gout flares, …

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回应：Didierlaurent 等人“关于重组带状疱疹疫苗 (RZV) 与痛风发作之间关联声明的澄清”

我们非常感兴趣地阅读了 Didierlaurent 等人 1 关于我们最近使用病例交叉设计报告接种疫苗与痛风发作风险之间关联的信函。 2 特别是，我们感谢作者提供的关于主动提供的不良事件的澄清在每次接种疫苗后 30 天内报告，包括痛风发作，痛风病例超过复发性痛风发作的报告。虽然这与我们的在线病例交叉研究有显着差异，该研究仅包括已知痛风患者并评估痛风复发，……