Dielectric barrier discharge (DBD) plasma treatments are more effective against Gram negative bacteria than Gram-positive bacteria. Effects of DBD plasma were compared on Salmonella Typhimurium and Staphylococcus aureus cells. Physical cell membrane integrity and function, deoxyribonucleic acid (DNA) oxidation, and intracellular reactive oxygen species (ROS) were measured. The difference in physical damage caused by plasma on Gram-negative and Gram positive bacteria implied a difference in cellular damage pattern, which may be due to differences in cell structure and composition. Antimicrobial particles in plasma react directly with the outer membranes of Gram-negative bacteria and eventually kill them; however, ROS produced from plasma first penetrated the cell wall and membrane of Gram-positive bacteria before reacting with internal cellular components and killing the bacteria.

中文翻译：

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鼠伤寒沙门氏菌和金黄色葡萄球菌之间的介电屏障放电血浆引起的细胞损伤差异。

介电势垒放电（DBD）等离子体处理比革兰氏阳性细菌更有效地抵抗革兰氏阴性细菌。比较了DBD血浆对鼠伤寒沙门氏菌和金黄色葡萄球菌细胞的影响。测量了物理细胞膜的完整性和功能，脱氧核糖核酸（DNA）氧化以及细胞内活性氧（ROS）。血浆对革兰氏阴性细菌和革兰氏阳性细菌造成的物理损伤的差异暗示了细胞损伤模式的差异，这可能是由于细胞结构和组成的差异所致。血浆中的抗菌颗粒直接与革兰氏阴性细菌的外膜反应，最终杀死它们。然而，